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7α-Hydroxylation of 27-hydroxycholesterol in human liver microsomes

✍ Scribed by Ingemar Björkhem; Björn Nyberg; Kurt Einarsson

Book ID
115740987
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
602 KB
Volume
1128
Category
Article
ISSN
0005-2760

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In a search for enzymes involved in the formation of bile acids from 27-hydroxycholesterol in humans, the metabolism of this and other side-chain oxygenated steroids was studied in human liver microsomes and mitochondria. The microsomal fraction contained enzyme(s) catalyzing 7a-hydroxylation of 27-