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79 Involvement of c-Jun N-terminal kinase (JNK) in the oxidative stress-induced tendon cell apoptosis and matrix degradation


Book ID
114400973
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
54 KB
Volume
7
Category
Article
ISSN
1440-2440

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## Abstract To explore the potential mechanisms of tendon degeneration, we investigated the role of c‐Jun N‐terminal Kinase (JNK) activation and the regulation of matrix metalloproteinase 1 (MMP1) in tendon matrix degradation under oxidative stress. JNK and MMP1 activity in samples from normal and