Pre-clinical evaluation of a methotrexat
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Angelika M. Burger; Gernot Hartung; Gerd Stehle; HannsjΓΆrg Sinn; Heinz Herbert F
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Article
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2001
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John Wiley and Sons
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French
β 127 KB
Methotrexate covalently bound to human serum albumin in a 1:1 molar ratio (MTX-HSA) is a new macromolecular drug which is currently being studied in phase I clinical trials by the German Association for Medical Oncology (AIO) Phase I/II study group. Previous studies have shown that MTX-HSA differs f