779 CXCL13-CXCR5 Signaling Is Required for the Anti-Tumor Immune Response in Colorectal Cancer

Evidence for a bias toward intracellular

Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display

✍ Rob C. Roovers; Edith van der Linden; Han Zijlema; Adriaan de Bruïne; Jan-Willem 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 948 KB

Many patients with colorectal carcinoma (CRC) mount a cellular as well as a humoral immune response to the tumor. To investigate the nature and specificity of the humoral immune response in a CRC patient, lymphocytes infiltrating the primary colorectal tumor and lymph nodes draining the tumor were u