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76Br-bromospiroperidol: A new tool for quantitative in-vivo imaging of neuroleptic receptors

✍ Scribed by B. Mazière; C. Loc'h; P. Hantraye; R. Guillon; N. Duquesnoy; F. Soussaline; R. Naquet; D. Comar; M. Mazière


Book ID
118340512
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
376 KB
Volume
35
Category
Article
ISSN
0024-3205

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2~-carbomethoxy-3~-(4-["Br]bromophenyI)tropane (f6Br]P-CBT) was prepared either by electrophilic substitution from the tributyl-stannyl derivative and peracetic acid as oxidant or by nucleophilic substitution from the iodo analogue (PCIT) and a Cu' assisted bromodeiodination exchange. After purifica