𝔖 Bobbio Scriptorium
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76. Multiple transcription start site clusters of mouse IL-1R1 gene

✍ Scribed by Q. Li; L. Zhu; H. Zhang; Q. Chen; N. Quan


Book ID
116276584
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
39 KB
Volume
23
Category
Article
ISSN
0889-1591

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## Abstract Interleukin‐1 (IL‐1) is a key pro‐inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Two major agonists, IL‐1Ξ± and IL‐1Ξ², bind to a single known functional type‐1 IL‐1 receptor (IL‐1RI) that associates wit