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757-4 Differential Regulation of Renal Cyclic Nucleotide Phosphodiesterases in Experimental Heart Failure

โœ Scribed by Roland R. Brandt; Holger Heinrich; Claudia C.S. Chini; Lawrence L. Aarhus; Thomas P. Dousa; John C. Burnett Jr


Book ID
119172070
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
128 KB
Volume
25
Category
Article
ISSN
1558-3597

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## Abstract During the perinatal period, lungs undergo changes to adapt to air breathing. The genes involved in these changes are developmentally regulated by various signaling pathways, including the cyclic nucleotide cAMP. As PDE4s are critical enzymes for regulation of cAMP levels, the objective