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75-6 - Presenilin genes in Alzheimer's diseases

โœ Scribed by E.I. Rogaev


Book ID
118512233
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
408 KB
Volume
42
Category
Article
ISSN
0006-3223

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The presenilins (PS-1 and PS-2) are 2 members of a novel family of genes encoding integral membrane proteins recently implicated in Alzheimer's disease (AD) pathology. To date, 43 mutations have been identified in PS-1 and 2 in PS-2 that lead to familial presenile AD (onset before age 65 years). The

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