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73 Expression of inducible nitric oxide synthase gene in airway epithelial cells in young children with CF


Book ID
118640216
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
92 KB
Volume
4
Category
Article
ISSN
1569-1993

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The bronchial epithelium in cystic ยฎbrosis (CF) expresses very low levels of the inducible form of nitric oxide synthase (iNOS). The product of iNOS, nitric oxide (NO), mediates anti-microbial effects and can reduce neutrophil sequestration in the lung. Heavy neutrophilic inยฎltration of the pulmonar