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722 POSTER Antitumor activity and pharmacokinetics of a novel PEGylated irinotecan in irinotecan-resistant colorectal tumours implanted in mice

✍ Scribed by M.A. Eldon; L. Antonian; C.M. Staschen; T.X. Viegas; M. Bentley; A. Singhal

Book ID: 118625363
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 69 KB
Volume: 5
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(07)70521-9

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## Abstract The authors reported in a previous study that NK012, a 7‐ethyl‐10‐hydroxy‐camptothecin (SN‐38)‐releasing nano‐system, exhibited high antitumor activity against human colorectal cancer xenografts. This study was conducted to investigate the advantages of NK012 over irinotecan hydrochlori