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71 Tolfenamic Acid Induces Apoptosis and Growth Inhibition in Head and Neck Cancer: Involvement of NAG-1 Expression

✍ Scribed by Kim, C.H.; Koh, Y.W.; Hong, H.; Kim, J.W.; Kang, S.U.; Chang, J.W.

Book ID: 123461845
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 56 KB
Volume: 48
Category: Article
ISSN: 0959-8049
DOI: 10.1016/S0959-8049(12)71869-5

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## Abstract Overexpression of the interleukin‐2 receptor (IL‐2R) α chain in tumor cells is associated with tumor progression and a poor patient prognosis. IL‐2Rα is responsible for the high affinity binding of the receptor to IL‐2, leading to activation of several proliferative and anti‐apoptotic i