706 A DESENSITIZATION TO ALPHA-2 INTERFERON COULD ACCOUNT FOR NON-RESPONSE IN CHRONIC HEPATITIS C
β Scribed by P. Sultanik; M. Andrieu; J. Gaston; G. Uze; S. Pol; V. Mallet
- Book ID
- 117378790
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 69 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0168-8278
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Ten patients with chronic hepatitis C, six of whom had not responded and four of whom had responded in a non-sustained fashion to interferon-alpha treatment alone, were given interferon alpha-2b and ribavirin in combination during 24 weeks. Interferon alpha-2b was given subcutaneously, at a dose of
## Abstract Hepatitis C virus (HCV) replication was assessed before and during alphaβinterferon (IFN) treatment in 22 antiβHCV positive patients with posttransfusion or sporadic chronic hepatitis (CH). Eleven patients were βrespondersβ and 11 patients βnonβrespondersβ to IFN. Thirteen antiβHCV nega