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70. Critical Involvement of Type 1 Interferons in Early Liver Ischemia-Reperfusion Injury

โœ Scribed by Andrew J. Vardanian; Elizabeth R. Benjamin; Danyun Zhao; Xiu-Da Shen; Feng Gao; Yuan Zhai; Jerzy W. Kupiec-Weglinski; Ronald W. Busuttil

Book ID
116703637
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
91 KB
Volume
144
Category
Article
ISSN
0022-4804

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๐Ÿ“œ SIMILAR VOLUMES

Type I, but not type II, interferon is c
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion
โœ Yuan Zhai; Bo Qiao; Feng Gao; Xiuda Shen; Andrew Vardanian; Ronald W. Busuttil; ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 480 KB

We have documented the key role of toll-like receptor 4 (TLR4) activation and its signaling pathway mediated by interferon (IFN) regulatory factor 3, in the induction of inflammation leading to the hepatocellular damage during liver ischemia/reperfusion injury (IRI). Because type I IFN is the major