7-Methyl-4-phenyl-8H-1,3,5,6-dithiadiazocin-2-one, an Eight-Membered Heterocycle with Chiral Conformation

✍ Scribed by Dr. G. Ege

• Publisher: John Wiley and Sons
• Year: 1967
• Tongue: English
• Weight: 271 KB
• Volume: 6
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.196706292

✦ Synopsis

tion of ( ) is explained by the strong reducing action of HGeC13 [?I. The alcohol ( ) is probably formed first and then condenses to give the ether (8). Under the influence of HGeC13 ethers can decompose to alkyl-or arylalkyl-trichlorogermanes and alcoholsW In fact, the reaction o f t h e alcohol (7) with HGeCI3 also gives the compound (6) (yield 89%). 0.6 1.5 1.2 ---0.5 1 .o 1.0 Other alcohols react similarly with trichlorogermane. Thus t-C4H90H gives t-C4HgGeCI3 (70 % yield), s -C ~H ~O H gives s -C ~H ~G ~C I ~ (42 % yield), n-C4H90H gives n-C4H9GeCI3 (46.5 % yield), and CH30H gives CH3GeCI3 (47 % yield).