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7 Apoptosis: Its role in drug sensitivity and resistance

✍ Scribed by J.A. Hickman


Book ID
116166764
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
71 KB
Volume
31
Category
Article
ISSN
0959-8049

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The purpose of this study was to determine whether expression of tissue transglutaminase (TG2) and caspase-3 proteins in drug-resistant breast carcinoma MCF-7/DOX cells would render these cells selectively susceptible to apoptotic stimuli. Despite high resistance to multidrug resistance (MDR)-relate