✦ LIBER ✦

6α-Fluoro- and 6α,9α-difluoro-11β,21- dihydroxy-16α,17α-propylmethylenedioxypregn-4-ene-3,20-dione: Synthesis and evaluation of activity and kinetics of their C-22 epimers

✍ Scribed by B.Arne Thalén; Bengt I Axelsson; Paul H Andersson; Ralph L Brattsand; Benkt Nylander; Lars-Inge Wickström

Book ID: 117213890
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 129 KB
Volume: 63
Category: Article
ISSN: 0039-128X
DOI: 10.1016/s0039-128x(97)00107-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and structure elucidation of p

Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α,9α-difluoro-11β,21-dihydroxy-16α,17α-propylmethylenedioxypregn-4-ene-3,20-dione, and related glucocorticosteroids

✍ Arne Thalén; Lars-Inge Wickström 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 186 KB

Fluorosteroids VII. Synthesis and biolog

Fluorosteroids VII. Synthesis and biological activity of derivatives of 6α-fluoro-16α,17α-isopropylidenedihydroxypregna-1,4-diene-11β, 21-diol--3,20-dione

✍ V. M. Ryzhkova; T. I. Gusarova; G. S. Grinenko; M. L. Gerasimova; T. M. Bykova; 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 600 KB

Excretion and distribution of 16,17-acet

Excretion and distribution of 16,17-acetonide of 21-acetoxy-3- (2'-chloroethoxy)-9α-fluoro-6-formyl- 11β,16α,17α-trihydroxy-3,5-pregnadien-20- one

✍ G. Baldratti; M. Menozzi; A. Minghetti 📂 Article 📅 1973 🏛 Elsevier Science 🌐 English ⚖ 488 KB

The crystal and molecular structure of 9

The crystal and molecular structure of 9α-fluoro-16α-methyl-11β,17,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate monohydrate

✍ Terzis, A. ;Theophanides, T. 📂 Article 📅 1975 🏛 International Union of Crystallography ⚖ 578 KB

X-ray study of budesonide: molecular str

X-ray study of budesonide: molecular structures and solid solutions of the (22S) and (22R) epimers of 11β,21-dihydroxy-16α,17α-propylmethylenedioxy-1,4-pregnadiene-3,20-dione

✍ Albertsson, J. ;Oskarsson, Å. ;Svensson, C. 📂 Article 📅 1978 🏛 International Union of Crystallography ⚖ 937 KB

Preparation of high specific activity tr

Preparation of high specific activity tritium labeled 6α,9,-difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-one, fluocinolone acetonide

✍ D. Zhong; Anita H. Lewin 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 289 KB

## Abstract Fluocinolone acetonide was tritiated by selective reduction of the 1,2‐double bond of the __O__‐protected analog under tritium, followed by re‐establishment of the 1,2‐double bond and deprotection. Protection of both hydroxyl functionalities was required. The product was obtained with s