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698 Critical Role of the Alpha-7 Nicotinic Acetylcholine Receptor in the Development of Colitis

✍ Scribed by Jean-Eric Ghia; Patricia Blennerhassett; Amber J. Park; Yikang Deng; Ryan Cornell; Stephen M. Collins

Book ID
119428335
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
67 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Abstract Pathological angiogenesis contributes to tobacco‐related diseases such as malignancy, atherosclerosis and age‐related macular degeneration. Nicotine acts on endothelial nicotinic acetylcholine receptors (nAChRs) to activate endothelial cells and to augment pathological angiogenesis. In