696 Regulation of MMP-13 (collagenase-3) by the transcription factor Pit-1
✍ Scribed by J. Sendón-Lago; S. Seoane; I. Ben-Batalla; B. Buelta-Sanmiguel; L.O. Gonzalez; F. Vizoso; R. Pérez-Fernández
- Book ID
- 119602473
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 47 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1359-6349
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Subnuclear compartmentation is postulated to play an important role in many aspects of nuclear metabolism. To directly test an application of this model to transcription factor function, we examined the subnuclear partitioning behavior of Pit-1, a tissue-specific, POU-class transactivator. Biochemic
## Abstract Interleukin‐1 (IL‐1)α is an autocrine/paracrine agent of the skeletal tissue and it regulates bone remodeling. Collagenase‐3 or matrix metalloproteinase (MMP)‐13 is expressed in osteoblasts and its expression is modulated by several cytokines including IL‐1α. Because the molecular mecha