A biliary HCO3โ umbrella constitutes a p
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Simon Hohenester; Lucas Maillette de Buy Wenniger; Coen C. Paulusma; Sandra J. v
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Article
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2011
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John Wiley and Sons
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English
โ 954 KB
Human cholangiocytes are continuously exposed to millimolar levels of hydrophobic bile salt monomers. We recently hypothesized that an apical biliary HCO ร 3 umbrella might prevent the protonation of biliary glycine-conjugated bile salts and uncontrolled cell entry of the corresponding bile acids, a