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69 Promoter of P53 target gene RTVP-1 is frequently methylated in transitional cell carcinoma of the bladder

✍ Scribed by F. Christoph; S. Weikert; H. Krause; K. Miller


Book ID
118646204
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
184 KB
Volume
4
Category
Article
ISSN
1569-9056

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## Abstract ## BACKGROUND. The secreted frizzled‐related protein 1 gene (__SFRP1__) encodes a Wnt/β‐catenin signaling antagonist and frequently is inactivated by promoter methylation in many tumors. However, the role of __SFRP1__ in hepatocellular carcinoma (HCC) is not clear. Therefore, the autho