✦ LIBER ✦

683 ESTRADIOL PROMOTES THE INVASIVE POTENCY OF PROSTATE CANCER CELLS IN A PARACRINE MANNER THROUGH STIMULATION OF PROSTATIC STROMAL CELLS

✍ Scribed by Yu, Lin; Shi, Jiandang; Wang, Chunyu; Klocker, Helmut; Mayer, Doris; Zhang, Ju

Book ID: 122568897
Publisher: Lippincott Williams and Wilkins
Year: 2010
Tongue: English
Weight: 46 KB
Volume: 183
Category: Article
ISSN: 0022-5347
DOI: 10.1016/j.juro.2010.02.1082

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## Abstract The androgen receptor (AR) is a ligand‐dependent transcription factor belonging to the steroid hormone receptor superfamily. Under normal conditions, in the absence of a ligand, the AR is localized to the cytoplasm and is actively transported into the nucleus upon binding of androgens.