✦ LIBER ✦

6,8-Dihydroxypurine: A novel growth factor for mammalian cells in vitro, isolated from a commercial peptone

✍ Scribed by Isao Yamane; Osamu Murakami

Book ID: 102309217
Publisher: John Wiley and Sons
Year: 1973
Tongue: English
Weight: 326 KB
Volume: 81
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040810216

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✦ Synopsis

Abstract

A substance promoting the growth of mammalian cells in vitro has been isolated from Bacto‐peptone (Difco Labs., Detroit) and identified as 6,8‐dihydroxypurine. This compound, which is isomeric with xanthine(2,6‐dihydroxypurine), enhances the growth of one Chinese hamster and some other cell lines; xanthine itself is inactive. The biological action of the compound is discussed.

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