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677 Claudin-1 Regulates E-Cadherin Expression Through ZEB-1 in Colon Cancer

✍ Scribed by Amar B. Singh; Moorthy Krishnan; Robert D. Beauchamp; Punita Dhawan


Book ID
119430329
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
46 KB
Volume
136
Category
Article
ISSN
0016-5085

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✍ Timothy R. McPhee; Paul C. McDonald; Arusha Oloumi; Shoukat Dedhar πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 958 KB

## Abstract Repression of E‐cadherin expression by the transcription factor, Snail, is implicated in epithelial to mesenchymal transition and cancer progression. We show here that Integrin‐Linked Kinase (ILK) regulates E‐cadherin expression through Poly(ADP‐ribose) polymerase‐1 (PARP‐1). ILK overex