## Abstract The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies indicate that blocking IGF-1R expression can inhibit tumor cell proliferation an
β¦ LIBER β¦
675 SILENCING OF BMI1 INHIBITED THE PROLIFERATION AND INVASIVENESS OF HUMAN HEPATOCELLULAR CARCINOMA CELLS AND INCREASED ITS SENSITIVITY TO 5-FLUOROURACIL
β Scribed by R. Zhang; L.B. Xu; C. Liu; X.-J. Yue; J. Wang
- Book ID
- 117379820
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 41 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0168-8278
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## Abstract Vitamin D (VD) protects against colon carcinogenesis by mechanisms not fully understood. We had earlier reported on the similarity in the biologic action of VD and that of the calciumβsensing receptor (CaSR) in human colon carcinoma cells. At the molecular level, the CaSR gene contains