6,7,14,15-Tetrahydro-15aH-azocino[1,2-a:6,5-b′]diindole. Synthesis of a novel pentacyclic ring system

✍ Scribed by Kittisak Sripha; Darius P. Zlotos; Stefan Buller; Klaus Mohr

• Book ID: 104254361
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 137 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01796-9

✦ Synopsis

In search of new lead structures for potent allosteric enhancers of antagonist binding to muscarinic M 2 receptors, a novel heterocyclic ring system, 6,7,14,15-tetrahydro-15aH-azocino[1,2-a:6,5-b%]diindole, has been synthesized. The new ring skeleton was obtained from indol-2-yl-acetic acid in three steps.