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6594 Phase II study of gemcitabine as a fixed dose rate infusion and S-1 combination therapy (FGS) in gemcitabine-refractory pancreatic cancer patients

✍ Scribed by Morizane, C.; Okusaka, T.; Ikeda, M.; Furuse, J.; Ohkawa, S.; Nakachi, K.; Suzuki, E.; Ueno, M.


Book ID
122064364
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
46 KB
Volume
7
Category
Article
ISSN
1359-6349

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A phase 1 study of fixed dose rate gemci
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## Abstract ## BACKGROUND. The combination of a fixed dose rate (FDR) infusion of gemcitabine and irinotecan may have a synergistic effect in the treatment of patients with advanced and metastatic pancreatic and biliary cancer. The current study was conducted to determine the dose‐limiting toxicit