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657: Intrapartum fetal heart rate characteristics of fetuses with trisomy 21 and congenital heart defects

โœ Scribed by Priyadarshini Koduri; Maria Adelaida Giraldo; Phillip Shlossman; Anthony Sciscione; Vincenzo Berghella; Suneet Chauhan

Book ID
113437408
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
386 KB
Volume
204
Category
Article
ISSN
1097-6868

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Unusual genotypes in the COL6A1 gene in
Unusual genotypes in the COL6A1 gene in parents of children with trisomy 21 and major congenital heart defects
โœ Gail E. Davies; Catherine M. Howard; Mathew J. Farrer; Michelle M. Coleman; Loui ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 424 KB

Collagen type VI is a candidate for a role in the pathogenesis of congenital heart defects (CHD) in Down's syndrome. Three restriction fragment length polymorphisms of the COL6A1 gene were used to determine COL6A1 genotypes in 50 families of affected children with trisomy 21 (29 with congenital hear