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6537 POSTER Selenite mediated cytotoxcicity in human lung cancer and the role of Thioredoxin reductase 1

✍ Scribed by Fernandes, A.P.; Selenius, M.; Capitanio, A.; Brodin, O.; Björnstedt, M.; Rundlöf, A.K.

Book ID: 121996812
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 58 KB
Volume: 5
Category: Article
ISSN: 1359-6349
DOI: 10.1016/S1359-6349(07)71365-4

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## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep