65-115 - Molecular analysis in Huntington's disease (HD) for predictive testing and clinical confirmation

Preimplantation diagnosis for Huntington

Preimplantation diagnosis for Huntington's disease (HD): clinical application and analysis of the HD expansion in affected embryos

✍ K. Sermon; V. Goossens; S. Seneca; W. Lissens; A. de Vos; M. Vandervorst; A. van 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views

Huntington's disease (HD) is an autosomal dominant disease characterized by motor disturbance, cognitive loss and psychiatric manifestations, starting between the fourth and the fifth decade, followed by death within 10-20 years of onset of the disease. The disease-causing mutation is an expansion o