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648 Fibulin-5 is down regulated in invasive growing primary prostate carcinoma cells

✍ Scribed by V. Jung; M. Saar; C.E. Hach; J. Kamradt; M. Stöckle; G. Unteregger


Book ID
119624579
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
16 KB
Volume
11
Category
Article
ISSN
1569-9056

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Down-regulation of the cell-surface adhesion molecule CD44 has been suggested to play an important role in tumor progression and metastasis of prostate cancer. CD44 is encoded by a gene that contains a CpG-rich region (CpG island) in its 5Ј regulatory sequence. We tried to assess whether hypermethyl