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637 EP300 – A miRNA Regulated Metastasis Suppressor Gene in Ductal Adenocarcinomas of the Pancreas

✍ Scribed by Mees, Soeren Torge; Mardin, Wolf A.; Wendel, Claudia; Baeumer, Nicole; Willscher, Edith; Senninger, Norbert J.; Colombo-Benkmann, Mario; Haier, Joerg


Book ID
122774552
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
146 KB
Volume
136
Category
Article
ISSN
0016-5085

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EP300—A miRNA-regulated metastasis suppr
✍ Soeren Torge Mees; Wolf Arif Mardin; Claudia Wendel; Nicole Baeumer; Edith Wills 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 451 KB

## Abstract Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDACs) are well known. This study investigates genetic and epigenetic data together with tumor biology to find specific alterations responsible for metastasis formation. Using 16 human PDAC cell