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631 The association between p53 alterations, ras mutations & tobacco smoking in non-small cell lung cancer (NSCLC)

โœ Scribed by Tammemagi, M.; Eskandarian, S.; Ozcelik, H.; Tsao, M.-S.; Mullen, B.; Johnston, M.; McLaughlin, J.; Casson, A.G.


Book ID
122874203
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
157 KB
Volume
18
Category
Article
ISSN
0169-5002

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Validated markers are needed to identify operable lung cancer patients with poor prognosis. About one-half of nonsmall-cell lung cancers (NSCLCs) carry a mutation in the p53 tumor-suppressor gene. We examined 101 NSCLC patients for surgical stage, completeness of resection, tobacco smoking, asbestos