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628 Lysosomal aspartic and cysteine proteinases regulate apoptosis of PC 12 cells

✍ Scribed by Kyoko Isahara; Yoshiyuki Ohsawa; Yasuo Uchiyama

Book ID
119523150
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
94 KB
Volume
28
Category
Article
ISSN
0168-0102

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Activation of proteolytic enzymes, including the caspase family of proteinases, is a feature characteristic of the apoptotic program. In the present study, we examined a potential role of intracellular proteinases in the death of neuronal PC12 and primary cultured rat microglial cells induced by 6-h