Transgenic mice replicating hepatitis B
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Leonie Halverscheid; Nina K. Mannes; Robert Weth; Manuela Kleinschmidt; Ursula S
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Article
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2008
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John Wiley and Sons
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English
β 262 KB
## Abstract Hepatitis B Virus (HBV) transgenic mice replicating the viral genome at high level but lacking expression of the small envelope protein (HBsAg) have been produced using a terminally redundant viral DNA construct (HBV 1.4). The generation of viable infectious progeny was dependent on sex