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621 INTERLEUKIN-33 INHIBITS HEPATITIS B VIRUS REPLICATION IN THE LIVERS OF TRANSGENIC MICE

✍ Scribed by Y.-F. Jiang; D.-M. Xu; W.-Y. Li; J.-Q. Niu


Book ID
117378706
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
51 KB
Volume
52
Category
Article
ISSN
0168-8278

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Transgenic mice replicating hepatitis B
✍ Leonie Halverscheid; Nina K. Mannes; Robert Weth; Manuela Kleinschmidt; Ursula S πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 262 KB

## Abstract Hepatitis B Virus (HBV) transgenic mice replicating the viral genome at high level but lacking expression of the small envelope protein (HBsAg) have been produced using a terminally redundant viral DNA construct (HBV 1.4). The generation of viable infectious progeny was dependent on sex