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62. A new route to iminazoles: synthesis of 2-ω-aminoalkyl derivatives of 4-methyliminazole

✍ Scribed by Ellinger, L. P. ;Goldberg, A. A.

Book ID
121282119
Publisher
The Royal Society of Chemistry
Year
1949
Weight
541 KB
Volume
0
Category
Article
ISSN
0368-1769

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A new convenient route for the synthesis
A new convenient route for the synthesis of 4(5)-(ω-aminoalkyl)-1 H-imidazoles
✍ Roeland C. Vollinga; Wiro M. P. B. Menge; Hendrik Timmerman 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 293 KB

## Abstract A new route for the synthesis of 4(5)‐(ω‐aminoalkyl)‐1 __H__‐imidazoles 1 on a preparative scale through C5 lithiation of a 1,2‐diprotected imidazole is described. When the described 1,2‐diprotected 5‐lithio‐imidazole is treated with a 1‐chloro‐ω‐iodoalkane 5, selective substitution of