The JMJD2A demethylase regulates apoptos
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Tae-Dong Kim; Sook Shin; William L. Berry; Sangphil Oh; Ralf Janknecht
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Article
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2012
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John Wiley and Sons
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English
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## Abstract JMJD2A is a transcriptional cofactor and enzyme that catalyzes demethylation of histone H3 lysines 9 and 36 and is overexpressed in human tumors, but its role in oncogenesis remains unclear. Here, we show that JMJD2A interacts with the tumor suppressor p53 both in vitro and in HCT116 co