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614Decoy of androgen-responsive element induces apoptosis in LNCAP cells

✍ Scribed by K. Sugimura; K. Kuratsukuri; K. Harimoto; T. Tanaka; H. Kawashima; T. Nakatani

Book ID
118646743
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
162 KB
Volume
4
Category
Article
ISSN
1569-9056

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Androgen ablation-induced prostate cancer regression is transient and ends with the regrowth of androgen-independent (AI) tumors. To mimic this evolution in culture, we chronically deprived an androgen-dependent (AD) prostate cancer cell line (LNCaP) of androgen, generating an AI derivative which re