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614 Association of genetic variants of the interferon alpha receptor-2 gene with outcome of treatment of persistant HCV infection

✍ Scribed by Simon Hellier; Angela J. Frodsham; Branwen J. Hennig; Suzanne Knapp; Mark Wright; Lyna Zhang; Howard C. Thomas; Mark Thursz; Adrian V.S. Hill


Book ID
119530520
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
131 KB
Volume
38
Category
Article
ISSN
0270-9139

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Variants in interferon-alpha pathway gen
✍ Tania Mara Welzel; Timothy R. Morgan; Herbert L. Bonkovsky; Deepa Naishadham; Ru πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 270 KB πŸ‘ 2 views

Combination treatment with pegylated-interferon-alpha (PEG IFN-␣) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may