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612 Mitochondrial-mediated apoptosis is induced by cationic polymers used in gene transfer

✍ Scribed by S.M. Moghimi; P. Symonds; A.C. Hunter; G. Debska; A. Szewczyk; J.C. Murray

Book ID: 118621794
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 145 KB
Volume: 2
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(04)80620-7

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## Abstract ## Background The extremely poor prognosis of patients with pancreatic ductal adenocarcinoma indicates the need for novel therapeutic approaches. The growth arrest and DNA damage‐inducible (Gadd) gene __Gadd45a__ is a member of a group of genes that are induced by DNA damaging agents a