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610 DEVELOPMENT OF A TEST FOR RCC BY DETECTION OF VHL MUTATIONS IN TISSUE AND FLUIDS OF PATIENTS WITH RENAL CELL CARCINOMA

✍ Scribed by Sreedharan, Shilpa; Arnold, Rebecca S; Kerley, Kimberly; Mercer, Kristina B; Ressler, Kerry; Master, Viraj A; Ogan, Kenneth; Roberts, David L; Pattaras, John G; Petros, John A


Book ID
122848700
Publisher
Lippincott Williams and Wilkins
Year
2013
Tongue
English
Weight
273 KB
Volume
189
Category
Article
ISSN
0022-5347

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## Communicated by Albert de la Chapelle To investigate the nature of somatic von Hippel-Lindau (VHL) mutations, we analyzed 173 primary sporadic human renal cell carcinomas for mutations of the VHL tumor suppressor gene, using polymerase chain reaction (PCR) and single-strand conformational polym