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6-Phenyl-6-alkylamido-5,6-dihydro-2H-pyran-2-ones: novel HIV protease inhibitors

✍ Scribed by Harriet W. Hamilton; Bradley D. Tait; Christopher Gajda; Susan E. Hagen; Donna Ferguson; Elizabeth A. Lunney; Alexander Pavlovsky; Peter J. Tummino

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
249 KB
Volume
6
Category
Article
ISSN
0960-894X

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The conformation of t-butyl 2-methoxy-5,
The conformation of t-butyl 2-methoxy-5, 6-dihydro-2 H-pyran-6-carboxylates and 6,6′- disubstituted 2-methoxy-5,6-dihydro-2H-pyran derivatives on the basis of 1H and 13 C NMR spectra
✍ Marek Chmielewski; Janusz Jurczak; Aleksander Zamojski; Halina Adamowicz 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 474 KB

## Abstract The ^1^H and ^13^C NMR spectra of __trans__‐ and __cis__‐__tert__‐butyl 2‐methoxy‐5,6‐dihydro‐2__H__‐pyran‐6‐carboxylates (1 and 2) and 6,6′‐disubstituted 2‐methoxy‐5,6‐dihydro‐2__H__‐pyrans (3‐7) have been recorded. HH and CH coupling constants are discussed in terms of the ^1^H~6~⇄^6^