The title compound, C~11~H~13~N~3~O, is a key intermediate in the synthesis of cardiotonic agents. The asymmetric unit consists of two molecules of the same enantiomer and the crystal packing is stabilized by intermolecular N—H...O hydrogen bonds.
6-Phenyl-4,5-dihydropyridazin-3(2H)-one
✍ Scribed by Abourichaa, Said ;Benchat, Noureddine ;Anaflous, Abderahmane ;Melhaoui, Amina ;Ben-Hadda, Taibi ;Oussaid, Boualem ;El Bali, Brahim ;Bolte, Michael
- Publisher
- International Union of Crystallography
- Year
- 2003
- Tongue
- English
- Weight
- 175 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1600-5368
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📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.004 A Ê R factor = 0.050 wR factor = 0.089 Data-to-parameter ratio = 12.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
Single-crystal X-ray study T = 296 K Mean '(C±C) = 0.002 A Ê R factor = 0.038 wR factor = 0.102 Data-to-parameter ratio = 12.3 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C 14 H 11 ClN 2 O, was synthesized by the reaction of N-(4-chlorophenyl)-2-nitrobenzylamine with triphosgene, induced by a low-valent titanium reagent (TiCl 4 /Zn). The dihydroquinazoline ring adopts a skew-boat conformation.