The 6-maleimidocaproyl hydrazone derivat
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Dirk Lebrecht; Andrea Geist; Uwe-Peter Ketelsen; JΓΆrg Haberstroh; Bernhard Setze
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Article
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2006
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John Wiley and Sons
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French
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## Abstract Doxorubicin causes a chronic cardiomyopathy in which genetic and functional lesions of mitochondria accumulate in the longβterm and explain in part the delayed onset of heart dysfunction. DOXOβEMCH a 6βmaleimidocaproyl hydrazone derivative of doxorubicin, is an albumin binding prodrug w