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6-isobutyrylaminopurine: A convenient building block for the synthesis of carbocyclic adenosine analogs

✍ Scribed by Jinglan Zhou; Kamal Bouhadir; Thomas R. Webb; Philip B. Shevlin

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 155 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00867-8

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✦ Synopsis

Readily available 6-isobutyrylaminopurine can replace either a primary or secondary OH group under Mitsunobu conditions and provide an effkient synthesis of carbocyclic analogs of adenosine. X-my data indicates that only tbe desired @-substituted derivatives of adenine are formed.

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