Suppression of Glutamine:Fructose-6-phos
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Tusty-Jiuan Hsieh; Tzu Lin; Pei-Chen Hsieh; Min-Chun Liao; Shyi-Jang Shin
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Article
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2011
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John Wiley and Sons
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English
⚖ 437 KB
## Abstract O‐linked __N__‐acetylglucosamine (O‐GlcNAc) protein modification has been implicated in the regulation of signaling pathways, cell function, and gene expression. Glutamine:fructose‐6‐phosphate amidotransferase‐1 (GFAT‐1) is the rate‐limiting enzyme in the hexosamine biosynthetic pathway