5E10: a prostate-specific surface-reactive monoclonal antibody
โ Scribed by Oskar W Rokhlin; George J Weiner; Michael B Cohen
- Book ID
- 117469134
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 81 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
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Prostate-specific antigen (PSA) is the most important tumor marker for early detection and monitoring of prostate cancer (PCa) patients. PSA is also elevated in many patients with benign prostatic hyperplasia (BPH). The study of the serum PSA forms, free PSA (f-PSA) and PSA complexed with a,-antichy
## Background: Radioimmunotherapy (rit) is a promising new modality for targeted, systemic delivery of radionuclides specifically to sites of androgen-independent metastatic prostate cancer. to be effective, rit requires an antibody with specificity for malignant cells and appropriate pharmacokinet