59 POSTER The combination of radiation and direct intratumoral injection of dendritic cells enhance systemic antitumor effect

Intratumoral injection of dendritic cell

Intratumoral injection of dendritic cells in combination with local hyperthermia induces systemic antitumor effect in patients with advanced melanoma

✍ Jun Guo; Jun Zhu; Xinan Sheng; Xiaopei Wang; Li Qu; Yan Han; Yuexiang Liu; Hui Z 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 351 KB

## Abstract Dendritic cells (DC) are potent antigen‐presenting cells that can present tumor antigens chaperoned by heat shock proteins (HSPs), while local hyperthermia (LHT) can increase the expression of HSPs. In this study, we determine if intratumoral injection of immature DC after LHT (LHT+IT‐D