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59 Mouse models for the study of pai function in tissue injury and repair

✍ Scribed by David Ginsburg; Dan Eitzman; Randy Westrick; Julie Pearson; Kris Dougherty; Elizabeth Nabel

Book ID
117439436
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
132 KB
Volume
11
Category
Article
ISSN
0268-9499

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## Abstract Germline mutations in DNA mismatch repair genes underlie one of the most common hereditary cancer predisposition syndromes known in humans, hereditary nonpolyposis colorectal cancer (HNPCC). Defects of the DNA mismatch repair system are also prevalent in sporadic colorectal cancers. The