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584 Induction of invasion in an organotypic oral cancer model by cobalt chloride, a hypoxia mimetic

✍ Scribed by I.J. Brusevold; C. Husvik; O. Schreurs; K. Schenck; M. Bryne; T.M. Søland

Book ID: 119602365
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 50 KB
Volume: 8
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(10)71385-9

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## Abstract Antibiotic forms of tetracycline exhibit antitumor activity in some tumor models. However, their low __in vivo__ efficacy and associated morbidity limit their long‐term application in cancer therapy. This report appraises the efficacy of doxycycline (DC) and non‐antimicrobial, chemicall