Synthesis and Some Biochemical Propertie
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David Loakes; Daniel M. Brown; Stephen A. Salisbury; Mark G. McDougall; Constant
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Article
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2003
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John Wiley and Sons
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German
⚖ 161 KB
## Abstract A novel nucleoside analogue is described based on the pyridazine ring system. The nucleoside was successfully incorporated into DNA __via__ both its phosphoramidite and 5′‐triphosphate derivatives. Enzymatically, the analogue behaves essentially as thymidine: it is a good substrate for